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Author

E. Khrameeva

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2 papers indexed here

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Oct 2026

The divergent 3D genome landscapes of aging and neurodegenerative mouse models.

Chromatin structure is essential for gene regulation and genome stability, as neurons must preserve their 3D genome organization throughout life. This structure gradually deteriorates with aging and is further disrupted in neurodegenerative diseases. To investigate whether aging and neurodegeneration share early chroma...

E. Kashuk, Dmitrii Smirnov, Ekaterina Eremenko et al. · 0 citations
Open access Sep 2026

A systematic evaluation of SIRT6 as a transcriptomic biomarker of aging

SIRT6 is a NAD+-dependent sirtuin that plays central roles in chromatin regulation, DNA repair, telomere maintenance, metabolic homeostasis, and inflammatory control. Although SIRT6 have long been implicated in aging because of its association with several hallmarks of aging, the available evidence remains largely cont...

E. Kashuk, A. Tarakānova, A. Malygina et al. · 0 citations

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