Frequency of BRCA1/2 mutations and the immunological profile of triple-negative breast cancer in young women: a systematic review
Triple-negative breast cancer (TNBC) in women ≤40 years old is characterized by aggressive behavior, a high frequency of BRCA mutations, and limited therapeutic options. The purpose of this study was to systematically review data on BRCA1/2 mutations and PD-L1 expression in young women with TNBC to assess molecular and...