Rare Cancer-Associated Mutations May Affect the AF1 Phosphoregulatory Domain of RARγ
Background/Objectives: Retinoic acid receptor γ (RARγ), encoded by RARG, is increasingly recognized as a cancer-associated regulator through aberrant expression in multiple solid tumors and recurrent gene rearrangements in acute myeloid leukemia. While the oncogenic relevance of RARγ is well established, the potential...