E. Korkotian

Impaired behavioral flexibility and coping strategy shifts in 5xFAD mice in the novel Destruction-Building Test

Introduction The assessment of early ethological markers of neurodegeneration in Alzheimer’s disease (AD) remains a pivotal task in preclinical research. This study evaluates the diagnostic potential of the “Destruction-Building Test” (DBT), a novel assay based on the innate manipulative behaviors of rodents–specifical...