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E. Küçüksille

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Open access Aug 2026

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron-binding ridge.

Frataxin is a mitochondrial iron-binding protein whose deficiency causes Friedreich's ataxia, yet the dynamic mechanisms by which this protein communicates iron-binding events to distal regions remain poorly understood. Traditional correlation-based analyses identify coupled residue motions but cannot resolve the direc...

Kevser Kübra Kırboğa, E. Küçüksille · 0 citations
Open access Oct 2026

Quantum Autoencoders for Network Anomaly Detection: A Comparative Benchmark with Classical Methods

The practical value of quantum machine learning for network anomaly detection remains unclear under controlled and comparable benchmarking conditions. This study evaluates a trash-qubit-based Quantum Autoencoder (QAE) against seven classical anomaly-detection methods on UNSW-NB15 using shared data partitions, preproces...

Gönül Altay, E. Küçüksille · 0 citations
Open access Jul 2026

Time Series Forecasting of Greenhouse Gas Emissions Using Deep Learning

S Sectoral findings suggest that short-term declines around 2020 are concentrated in transport and energy-related sectors, while agriculture and industrial/process-related emissions remain relatively stable.

Damla Yalçıner Çal, E. Küçüksille · 0 citations
Open access Sep 2026

From DevOps to XOps: an agent-driven reference architecture for autonomous enterprise operations

XOps is proposed, a five-layer reference architecture integrating PlatformOps, DataOps, MLOps and AIOps beneath an Agentic Orchestration layer with Policy-as-Code governance, together with a continuous-time Markov chain model quantifying the availability effect of agent-driven remediation.

Mete Köse, E. Küçüksille · 0 citations

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