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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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E. Lander

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Open access Sep 2026

Quantitative changes in 3D contact predict changes in enhancer-promoter regulation upon cohesin depletion

Enhancers are drivers of gene regulation thought to act via 3D interactions with promoters. However, genome-wide cohesin depletion causes only limited changes in gene expression, despite widespread loss of contact domains, raising questions about how 3D contacts and cohesin influence enhancer function. Here, we intro...

Philine Guckelberger, Benjamin R. Doughty, Suhas S. P. Rao et al. · 0 citations

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