Bispecific Antibodies for Acute Myeloid Leukemia: From Bone Marrow Immune Niche to Clinical Translation
The biological rationale for immunotherapy in AML is summarized, with a focus on the role of the BM microenvironment and immune dysregulation, and the structural and functional properties of IgG-like and non-IgG-like bsAbs and key antigenic targets under clinical investigation are discussed.