Open access
Sep 2026
Dynamic expression range expansion of ECF sigma factor-dependent synthetic regulons by promoter context engineering
The results establish promoter environment engineering as a robust strategy for expanding the dynamic range of orthogonal ECF regulatory systems and facilitate the scalable design of synthetic transcriptional programs in bacteria.
C. Rauch, Doreen Meier, Vinca N. Seiler et al.
· bioRxiv · 0 citations