Open access
Aug 2026
The Tissue Factor-TFPI Pathway as a Therapeutic Target in Bleeding Disorders of Unknown Cause.
Findings identify dysregulation of the TF-TFPI axis as a potential pathophysiological mechanism underlying bleeding in a subset of patients with BDUC and highlight TFPI inhibition and rFVIIa administration as potential therapeutic approaches.
E. M. Manzano, P. Acuña, M. Martin-Salces et al.
· Journal of Thrombosis and Ha... · 0 citations