Aug 2026
Osteogenic Differentiation Restores Physiological Mineralization Pathways in SaOS-2 Osteosarcoma Cells.
Osteosarcoma, the most common primary malignant bone tumor, is characterized by disruptions in osteogenic differentiation and matrix mineralization. In physiological bone formation, mesenchymal stem cells differentiate into osteoblasts and coordinate the deposition of hydroxyapatite, the principal mineral component of...
Francesca Rossi, M. Rossi, L. Anconelli et al.
· Acta Biomaterialia · 0 citations