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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

E. Manning

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Review Open access Aug 2026

Oxygen Delivery in the Adult Intensive Care Unit with a Focus on Hyperoxic Acute Lung Injury Pathogenesis and Clinical Manifestations.

High oxygen damages human lung, called hyperoxic acute lung injury (HALI). HALI pathogenesis involves formation of reactive oxygen species (ROS) which overwhelm antioxidant mechanisms and lead to alveolar epithelial and endothelial cell death and interstitial inflammation. Resultant alveolar flooding causes ventilation...

Zachary M. Harris, E. Manning · 0 citations
Aug 2026

A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity

Time-resolved single-cell RNA sequencing across 16 conditions spanning age, sex, and four stages of influenza infection in mice generates a high-resolution atlas, revealing how infection status of the cell, age, and sex interact to drive persistent inflammation and impaired resolution.

Lu-Jia Chen, Aodong Qiu, Jooyoung Kim et al. · 0 citations

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