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Author

E. Mederos-Luis

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2 papers indexed here

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Open access Oct 2026

Epigenome-Wide Association Study of the Upper-Airway Microbiome Involved in Asthma Exacerbations

Rationale: The role of DNA methylation (DNAm) markers in the upper-airway microbiome related to asthma exacerbations despite inhaled corticosteroid (ICS) treatment is unexplored. Objectives: To identify whole-blood DNAm markers associated with the upper-airway microbiome related to asthma exacerbations despite ICS trea...

E. Castillo-Vargas, M. Martin-Almeida, A. Bozack et al. · 0 citations
Open access Sep 2026

Blood epigenetic remodeling in asthma associated with biologic therapy

Background. Polygenic risk scores (PRS) capture inherited susceptibility to asthma, whereas methylation risk scores (MRS) may reflect disease-associated epigenetic variation. We assessed whether these scores differ in patients requiring biologic therapy and whether MRS change after mepolizumab initiation. Methods. Cros...

M. Martin-Almeida, J. Pérez-García, E. Martín-González et al. · 0 citations

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