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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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E. Mendenhall

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Open access Aug 2026

Trex-QTL: A mixture-model for identification of genetic effects with global effects on molecular phenotypes

While thousands of cis expression quantitative trait loci (cis-eQTLs) have been reliably identified, detecting trans-eQTL effects has proven to be challenging due to insufficient statistical power, lack of comparable tissues and cohorts, and low reproducibility across studies. Here, we present Trex-QTL, a novel trans-e...

Cynthia Wu, Andrey V. Bzikadze, Tian-Yao Xu et al. · 0 citations

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