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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

E. Moses

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Open access Oct 2026

Polygenic risk scores for hypertensive disorders of pregnancy and later-life cardiovascular disease in women

Objectives: To investigate whether genetic predisposition to hypertensive disorders of pregnancy (HDP), measured using polygenic risk scores (PRS), is associated with subsequent cardiovascular disease (CVD) outcomes in analyses stratified by HDP history. Study design and main outcome measures: This population-based coh...

G. Krishnamurthy, J. A. Temple, M. A. Ahmed et al. · 0 citations
Open access Aug 2026

Integration of lipidomic and polygenic risk scores within contemporary clinical cardiovascular risk assessment pathways: a multi-cohort development and validation study

Summary Background Guideline-recommended clinical risk scores such as AusCVDRisk underestimate cardiovascular disease (CVD) risk in a substantial proportion of individuals who later experience events, with up to 65% initially classified as low or intermediate risk. This limitation is most consequential in the intermedi...

Aleksandar Dakic, Jing-Qin Wu, Ting-Ting Wang et al. · 0 citations

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