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Open access Sep 2026

Spatial proteomics reveals carboxysome adaptation and mitochondrial proteome in Paulinella chromatophora.

The Rhizarian amoeba Paulinella chromatophora represents a unique case of primary endosymbiosis, which has acquired photosynthetic organelles (chromatophores) independently of the endosymbiosis event that gave rise to plastids. Using localization of organelle proteins by isotope tagging following differential centrifug...

Lawrence Rudy Cadena, T. Lenz, Christian Stiebeling et al. · 0 citations
Open access Sep 2026

A step toward synthetic endosymbiosis: introducing Escherichia coli and the trypanosomatid endosymbiont Candidatus Kinetoplastibacterium crithidii into mammalian cells using a polyethylene glycol-based fusion protocol

Synthetic endosymbiosis, the deliberate introduction of bacteria into eukaryotic host cells, provides a tractable model for how endosymbiotic relationships become established, and a route to cells with new metabolic capabilities that never evolved naturally in that lineage. Current methods for introducing bacteria into...

Rudvi Pednekar, Natascha A. van Geelen-Kuenzel, Carroll M. C. Diehl et al. · 0 citations

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