Malaria control has become dependent on two technologies whose limitations are now well documented: light microscopy, which cannot reliably detect the low-density infections that sustain transmission, and antigen-detecting rapid diagnostic tests, whose principal target is being deleted from parasite populations under d...
Robinson Ndifrekeabasi Itek, E. Onosakponome· Microbiology Research Journa...· 0 citations
Clustered regularly interspaced short palindromic repeats (CRISPR) nucleases with collateral, sequence-activated nuclease activity have been proposed as a route to molecular-grade sensitivity at the point of care, and the proposal is unusually consequential for neglected tropical parasitic diseases, where control and e...
Chidi L. C. Ndukwu, E. Onosakponome· South Asian Journal of Resea...· 0 citations
Emerging and zoonotic parasitic diseases are sustained by transmission systems that cross human, domestic-animal, wildlife, vector, food and environmental compartments. Molecular methods can reveal parasite identity, genetic diversity and connectivity across those compartments, but technological sensitivity alone does...
E. Onosakponome, Chidi L. C. Ndukwu, Sonrandein Ditimi Bodensibari· South Asian Journal of Resea...· 0 citations
Genomic surveillance is reshaping resistance monitoring, but its public-health value depends on sustained investment in decentralized sequencing capacity, data-sharing infrastructure that respects national data sovereignty, and stronger links between genomic findings and revisions to treatment and vector-control polici...
Esiere RoseMary Kaiso, E. Onosakponome· Asian Journal of Research in...· 0 citations
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