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E. P. Coskun

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Open access Sep 2026

Autopsy findings in Alzheimer's disease clinical trial participants demonstrate a high frequency of off-target coexisting pathologic features

Background Having multiple comorbid neuropathologic features may confound the results of interventional trials that were designed to target a specific pathophysiologic mechanism in Alzheimer’s disease (AD) and or related dementias (ADRD). However, it is unknown what percentage of individuals undergoing AD/ADRD interven...

E. P. Coskun, Justin M. Barber, Lauren Bojarski et al. · 0 citations

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