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Open access Oct 2026

catena-Poly[[diaqua(nitrato-κO)(nitrato-κ2O,O′)(μ-2,5-bis[(pyridin-3-yl)ethynyl]thiophene-κN:κN′)cadmium(II)] hydrate]

The reaction of Cd(NO3)2·4H2O with the fluorescent ditopic N-donor ligand 2,5-bis[(pyridin-3-yl)ethynyl]thiophene (L) afforded the new coordination polymer {[Cd(L)(H2O)2(NO3)2]∙1.25H2O}n (1). Single-crystal X-ray diffraction analysis revealed that the CdII centre is heptacoordinated and adopts a distorted pentagonal-bi...

E. Podda, J. Orton, S. Coles et al. · 0 citations
Oct 2026

Dual inhibitors of SARS-CoV-2 Nsp13 helicase functions with broad anti-hCoV activity and combination effects with approved antivirals.

The SARS-CoV-2 non-structural protein 13 (nsp13) is a highly conserved helicase essential for viral replication and immune evasion. Its conservation across coronaviruses makes it an attractive target for the development of broad-spectrum antiviral agents. Hence, we rationally designed and synthesised 42 novel 2-iminoth...

Erica Sanna, A. Corona, S. Distinto et al. · 0 citations

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