Open access
Sep 2026
Engineered probiotics for tumor-targeted combination chemoimmunotherapy
The approach integrates enzyme/prodrug therapy and immunotherapy into a single bacterial delivery system, overcoming key limitations of conventional therapies by providing a rationally designed framework for spatially controlled chemoimmunotherapy.
Zao-Feng Yang, Jong-Seong Im, Noah Chen et al.
· Science Translational Medici... · 0 citations