Author

E. Rudzinski

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Sep 2026

Abstract C018: DNA methylation profiling reveals novel rhabdomyosarcoma subsets with distinct histologic, genetic and clinical properties

Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma and can be divided into two major subtypes: fusion-positive (FP) RMS, which most commonly involves the PAX3::FOXO1 or PAX7::FOXO1 fusion gene, and fusion-negative (FN) RMS, which lacks these gene fusions. Previous DNA methylation studies have sho...

Wen-Yue Sun, J. Lopez-Nava, J. Shern et al. · Cancer Research · 0 citations

Sep 2026

Abstract A005: Preliminary results from STRIvE-01, Arm B: A phase I study of EGFR806 x CD19 CAR T cell immunotherapy for recurrent/refractory solid tumors in children and young adults

The epidermal growth factor receptor (EGFR) is associated with aggressive neoplastic disease, chemotherapy resistance, and increased metastatic potential in solid neoplasms. Approximately 20-30% of pediatric solid tumors (ST) express EGFR, enriched for soft tissue sarcomas (STS). The unique EGFR monoclonal antibody (...

Catherine M. Albert, N. Pinto, Molly R. Taylor et al. · Cancer Research · 0 citations