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E. S. Leite

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Open access Oct 2026

Drug repurposing-inspired design of miconazole-based 1,2,3-triazoles as antichagasic agents.

Drug-repurposing strategies have been widely explored to accelerate the development of new treatments for Chagas disease, leveraging compounds with previously established safety profiles. Among these, azole antifungals have attracted attention due to their inhibitory activity against 14-α-lanosterol demethylase (CYP51)...

Mariana Araújo Marques, Augusto Vieira Pontes Silva, R. C. F. M. Reis et al. · 0 citations

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