A Hybrid Bioprinting-Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity.
The intrinsic heterogeneity of solid tumors remains a crucial barrier to understanding cancer biology and predicting therapeutic outcomes. Here, we introduce a scalable and versatile biofabrication platform that enables the controlled assembly of multitype spheroid arrays (MSA) within standard culture microplates. By p...