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Author

E. Shigetomi

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Review Sep 2026

[Gq-GPCR upregulation in reactive astrocytes: implication for neurological disorders].

The P2Y1R-IGFBP2 signaling axis is identified as a common pathological feature of reactive astrocytes across brain diseases and IGFBP2 is established as a novel glial-derived factor that could promote neuronal hyperexcitability.

E. Shigetomi, Schuichi Koizumi · 0 citations

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