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E. Sierecki

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Open access Sep 2026

Seed amplification of released alpha-synuclein strains reveals genotype-specific differences in Parkinson’s disease neurons

Findings indicate that genotype-specific cellular responses differentially shape the structural properties of released α-syn in a manner that determines amplification responses, enabling inter-group discrimination at the single-molecule level.

Jessica Chedid, Yuan Tang, K. Law et al. · 0 citations

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