Experimental Microglial Secretome Screening in Rat Organotypic Brain Slice Cultures.
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and is characterized by extensive interactions between tumor cells and glioblastoma-associated microglia and macrophages (GAMM). In the peritumoral region, where residual glioma cells contribute to recurrence, resident microglia represent the...