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Author

E. Susaki

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Open access Sep 2026

Highly plastic macrophage niches orchestrate acquired quiescence and reactivation in breast-cancer bone metastasis

These findings uncover CAF–bone-marrow cross-talk as a therapeutic target linking stromal inflammation, immune remodeling, and metastatic progression as a therapeutic target linking stromal inflammation, immune remodeling, and metastatic progression.

Yasuto Takeuchi, Hua-Zi Zhang, T. Murayama et al. · 0 citations
Open access Jul 2026

Colorectal cancer co-opts an epidermal wound healing program during metastasis to generate disseminated tumor cells

It is shown that CRC cells transiently adopt a wound-healing program normally used by epidermal keratinocytes during tissue repair to enable metastatic dissemination, and this state is reversible, as cells reacquire primary tumor–like characteristics upon colonization of distant organs.

M. Sakahara, Takuya Okamoto, Kohei Kumegawa et al. · 0 citations

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