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Open access Sep 2026

The Converging Roles of DNA Damage Resolution and Redox Dysregulation in Plasma Cell Transformation During the Evolution of Multiple Myeloma

Increasing evidence indicates that dysregulated DNA damage response (DDR) pathways and persistent oxidative stress contribute to genomic instability, increase mutational burden, and promote disease progression. This study investigated the interplay between DDR-related parameters and redox status throughout Multiple Mye...

Panagiotis Malamos, Konstantinos Koutoulogenis, M. Gavriatopoulou et al. · 0 citations
Review Sep 2026

Monoclonal Antibodies and Antibody-Drug Conjugates: Expanding the Therapeutic Arsenal in Multiple Myeloma.

Monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) have significantly expanded the therapeutic landscape of multiple myeloma (MM), contributing to deeper and more durable responses and meaningful survival benefits across the continuum of the disease. CD38-targeting mAbs are now integral to frontline regim...

I. Ntanasis-Stathopoulos, E. Terpos, M. Dimopoulos · 0 citations

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