Author

E. V. van Bodegraven

2 papers indexed here

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Open access Sep 2026

A human iPSC-based perfusable and membrane-free neurovascular unit-on-chip connecting brain organoids to the blood–brain barrier

The blood–brain barrier (BBB) protects the central nervous system by restricting entry of harmful blood-borne factors, but this selectivity actively limits delivery of therapeutics to the brain. Because BBB function is shaped by dynamic interactions within the neurovascular unit (NVU), particularly between brain endoth...

Henrique Nogueira Pinto, Lois Kistemaker, Mikhail Ponomarenko et al. · Lab on a Chip · 0 citations

Open access Sep 2026

Vimentin loss inhibits DNA damage responses and promotes cancer cell survival.

Vimentin intermediate filaments are a hallmark of aggressive tumours and are widely linked to invasion and EMT, yet how vimentin-dependent mechanics shape genome maintenance and therapy response is unclear. Here we show that vimentin, particularly under compressive load, promotes DNA repair competence. In contrast, vim...

Elvira Infante, E. Terriac, Matthieu Gélin et al. · EMBO Reports · 0 citations