E. V. Zarov

Comparison of the genetic profiles of Burkholderia cenocepacia in patients with cystic fibrosis before and during targeted therapy

Introduction. Cystic fibrosis is an autosomal recessive genetic disorder caused by mutations in the CFTR gene and characterized by involvement of the exocrine glands. Of particular clinical importance for patients with cystic fibrosis are bacteria Burkholderia cenocepacia, due to their propensity for persistence and th...