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Author

E. Vettorazzi

2 papers indexed here

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Open access Oct 2026

Adjuvant chemotherapy with cisplatin and gemcitabine compared to standard of care after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1/AIO-HEP-0112 trial).

BACKGROUND Despite curative resection and adjuvant capecitabine, about 50% of biliary tract cancer (BTC) patients have tumour recurrence or die within two years. Combination chemotherapy with cisplatin and gemcitabine (CisGem) is an established palliative chemotherapy regimen BTC, which has been evaluated in the adjuva...

A. Stein, J. Bridgewater, H. Klümpen et al. · 0 citations
Open access Oct 2026

Individualized Cardiac Index-Guided Hemodynamic Therapy in High-Risk Patients Undergoing Elective Major Abdominal Surgery: The PELICAN Randomized Clinical Trial.

Importance It remains unclear if intraoperative hemodynamic therapy should be guided by cardiac index. Objective To evaluate whether individualized cardiac index-guided hemodynamic therapy vs routine hemodynamic therapy improves outcomes in high-risk patients undergoing elective major abdominal surgery. Design, Set...

B. Saugel, Agnes S. Meidert, C. S. Meyhoff et al. · 0 citations

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