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Author

E. Vilas-Boas

2 papers indexed here

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Review Open access Aug 2026

Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes

Two of the main intracellular signaling molecules in pancreatic β-cells are calcium (Ca2+) and reactive oxygen species (ROS). Ca2+ signaling is essential for regulating energy metabolism, insulin secretion, and the modulation of key factors involved in β-cell survival and function. In parallel, redox signaling also aff...

Lucas Rafael Pereira Camara, E. Vilas-Boas · 0 citations
Open access Aug 2026

EP393 - ECE_1290 - Modulation of mitochondrial function and Ca2⁺ dynamics by semaglutide in pancreatic beta cells

GLP-1 receptor agonists such as semaglutide regulate multiple stimulus–secretion coupling components in pancreatic beta cells, integrating metabolic, ionic, and secretory pathways. These agents influence mitochondrial ATP production, membrane excitability, and Ca2⁺ handling, all of which are essential for insulin sec...

É. Vogt, E. Vilas-Boas, Debora Rocha et al. · 0 citations

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