Open access
Sep 2026
Functional diversification of two Lon homologs enhances stress adaptation in Pseudomonas aeruginosa
It is shown that AsrA has evolved distinct substrate preferences and stress-responsive functions while retaining substantial functional overlap with Lon, demonstrating how duplication of a conserved protease can generate specialized regulatory functions through differential expression and substrate preference, expandin...
Aswathy Kallazhi, Max Louski, Wissal Bakri et al.
· bioRxiv · 0 citations