291. Altered inhibitory/excitatory neurotransmitter balance across subtypes of depression
Abstract Background Neurotransmitter alterations in the main inhibitory and excitatory systems, GABA and glutamate, have frequently been reported in major depressive disorder (MDD) (Kalueff and Nutt, 2007; Godfrey, 2025). Disruptions in the inhibitory/excitatory (I/E) balance may be linked pathophysiological mechanisms...