Author

E. Wolvetang

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Open access Aug 2026

Oligodendrocyte Enriched Brain Organoids Reveal Impaired Oligodendroglial Maturation and Altered Neural Network Activity in Down Syndrome

It is shown that trisomy 21 disrupts early developmental stages and establish oligodendrocyte enriched brain organoids as a human model to investigate the developmental origins of white matter and network dysfunction in DS.

Marta Boira Marti, Sean D. Morrison, Selin Pars et al. · bioRxiv · 0 citations