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E. Y. Sitnikova

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Open access Oct 2026

Current Understanding of the Molecular Mechanisms of Resistance to Targeted Anti-HER2 Breast Cancer Therapy

This lecture summarizes current evidence on the molecular and genetic mechanisms of resistance to HER2targeted breast cancer (BC) therapies. Despite marked improvements in HER2-positive BC treatment, the efficacy of targeted therapy remains suboptimal. Within the first two years after completing combined therapy, 10-15...

O. Bragina, E. Y. Sitnikova, A. A. Nesynov et al. · 0 citations

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