Ethambutol Population Pharmacokinetics and Pharmacodynamics from a Phase 3 Confirmatory Trial for the Treatment of Tuberculosis
Background: Ethambutol, a longstanding treatment for tuberculosis, lacks comprehensive pharmacokinetic data, particularly regarding covariates affecting exposure and their link to treatment outcomes. Using the largest data to date from Study 31/AIDS Clinical Trials Group A5349, we aimed to characterize ethambutol pharm...