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Review Open access Sep 2026

Phage bioinformatics tools: a review of computational approaches for bacteriophage research

This review synthesizes the field through the lens of three successive computational paradigms: sequence homology, bounded by database completeness; machine learning, constrained by labelled training data; and foundation models, which now achieve Matthews correlation coefficients above 0.95 and raise functional annotat...

Sean Jia Le Pang, Soon Keong Wee, E. P. Yap · 0 citations
Open access Aug 2026

Bacterial Lysis Observation Over Time Assay (BLOTS) for High‐Throughput Isolation, Sequencing, and Characterization of Bacteriophages

A robust and scalable field‐to‐genome workflow that leverages laboratory automation to screen environmental samples against a comprehensive 188‐strain bacterial host library using a 384‐well plate format is developed.

Sean Jia Le Pang, Soon Keong Wee, Bobby Guo Wei Lee et al. · 0 citations

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