Ebrahim-Alkhalil M. A. Ahmed

Palladium-Catalyzed N-Fluoroallylation of Sulfoximines and Benzophenone Imine with gem-Difluorinated Cyclopropanes.

Sulfoximines are indispensable core scaffolds in medicinal chemistry and organic synthesis. N-Allylation represents a powerful strategy for enriching the structural diversity of sulfoximines, while fluorine incorporation can effectively enhance the lipophilicity and metabolic stability of functional molecules. Herein,...