Open access
Jul 2026
Mapping Functional Tumor Suppressor Networks in Esophageal Adenocarcinoma Using In Vivo CRISPR Screening and Perturb-sequencing
Findings provide a unifying framework for genomic heterogeneity in EAC, uncover underappreciated tumor suppressor pathways, and establish a resource to guide mechanistic and translational studies aimed at improving treatment strategies in this aggressive cancer.
Ebtihal Mustafa, Katherine Papastratos, Ka-Meng Wu et al.
· bioRxiv · 0 citations