Author

Edith Heard

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Open access Sep 2026

X-inactivation escapee domains are CTCF-cohesin independent chromatin compartments

It is shown that facultative escape regions are self-sustaining compartments of active chromatin enriched in H3K27 acetylation and depleted in H3K27 methylation, with the magnitude of compartment strength scaling up with the degree of transcriptional activity on the inactive X chromosome.

Antonia Hauth, A. Loda, Nikolai S. Bykov et al. · bioRxiv · 0 citations