Immune profiling of anti-SSA–positive at-risk individuals reveals increased type I IFN activity preceding lymphocyte abnormalities in Sjögren’s disease
Identifying immune features that distinguish asymptomatic autoantibody-positive at-risk individuals from patients with established autoimmune disease is key to understanding the evolution from autoreactivity to established autoimmune disease. This study investigated immune characteristics of anti-SSA–positive at-ri...