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Author

Eduard Sabidó

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Open access Jul 2026

A comprehensive HA-tagged PRC1 toolkit enables standardized chromatin profiling and proteomic analysis in Drosophila melanogaster

It is shown that endogenous HA tagging preserves protein expression, chromatin localization, and genome-wide binding profiles, enabling direct comparison using a common antibody to analyze distinct PcG subunits, and provides a platform for standardized analysis of Polycomb function and chromatin regulation.

L. Fritsch, V. Loubiere, Axelle Donjon et al. · 0 citations
Open access Mar 2025

Diversity and evolution of chromatin regulatory states across eukaryotes

A combinatorial indexing ChIP-seq method is developed to simultaneously profile specific hPTMs across diverse eukaryotic lineages, suggesting that while core hPTMs are ancient and broadly conserved, their functional readout has diversified throughout eukaryotic evolution, shaping lineage-specific chromatin landscapes.

Cristina Navarrete, Sean A. Montgomery, Julen Mendieta et al. · 11 citations · ⚡4

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