Author

Edward E Graves

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Open access Aug 2026

CD4+ T-Cells Drive Triple Negative Breast Cancer Recurrence via Non-Canonical TGFβ Signaling

Radiation therapy is a cornerstone of breast cancer treatment and reduces recurrence overall. However, patients with triple negative breast cancer (TNBC) continue to experience recurrence at higher rates than patients with other subtypes, especially when immunocompromised. While CD8⁺ T-cells are known to mitigate recur...

McKenzie A. Mayeaux, Benjamin P. Altman, Benjamin C. Hacker et al. · bioRxiv · 0 citations

Review Aug 2026

Biomarker-Driven Insights into Immune Checkpoint Inhibitor Therapy in Small-Cell Lung Cancer.

The pivotal roles of biomarkers in SCLC are highlighted, underscoring their contributions to treatment resistance across tumor-intrinsic mechanisms, immune landscape of the tumor microenvironment (TME) and systemic host factors.

Shu-Xing Wang, Xin-rui Zhao, Yue-Yue Zeng et al. · Critical reviews in oncology... · 0 citations