Author

Efthymios Poulios

2 papers indexed here

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Review Open access Sep 2026

Hyperforin as a Multifunctional Specialized Metabolite of Natural Origin for Chronic Diseases: From Molecular Mechanisms to Clinical Translation

Hyperforin, a polyprenylated acylphloroglucinol and major bioactive constituent of Hypericum perforatum L. (H. perforatum, St. John’s Wort), has attracted considerable interest because of its pleiotropic pharmacological properties. Although historically investigated primarily for its contribution to the antidepressant...

Efthymios Poulios, Souzana K. Papadopoulou, Exakousti-Petroula Angelakou et al. · Current Issues in Molecular... · 0 citations

Review Open access Jul 2026

Natural Products in Modern Drug Discovery: Advances, Challenges and Emerging Technologies

A comprehensive and mechanistic overview of natural products as lead compounds, emphasizing their chemical characteristics, biological relevance, sources, mechanisms of action, and integration into modern drug discovery pipelines is provided.

Souzana K. Papadopoulou, Efthymios Poulios, Fotios Tsopelas et al. · Scientia Pharmaceutica · 2 citations