ABSTRACT The prevalence of non-susceptibility to ceftolozane-tazobactam (C/T) among Pseudomonas aeruginosa remains low, but novel mechanisms of C/T resistance are of concern. Herein, we describe a novel P. aeruginosa genotype associated with high-level C/T resistance (>256/4 µg/mL) in a single patient. Whole-genome seq...
Preeti Garai, Sophia H. Nozick, Caroline C. Jozefczyk et al.· Antimicrobial Agents and Che...· 0 citations
BACKGROUND
Diphtheria remains endemic in Pakistan with cases increasing following the COVID-19 pandemic despite on-going vaccination programs. This study analyzes the genomic diversity, virulence and antimicrobial resistance patterns of pharyngeal diphtheria strains collected during the Karachi outbreak.
METHODS
C. d...
Sobia Khan, S. Irfan, J. Ashraf et al.· International Journal of Inf...· 0 citations
Children typically experience milder SARS-CoV-2 infection than adults, yet a subset—especially those with immune compromise—develop persistent infection. This study examined clinical characteristics and intra-host viral evolution in pediatric patients with prolonged COVID-19, comparing immunocompetent and immunoc...
Charlie R. Boyle, Tien Doan, Estefany Rios-Guzman et al.· Journal of the Pediatric Inf...· 0 citations
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