Author

Ehsan Lotfi

2 papers indexed here

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Open access Sep 2026

Identification of Key Genes and Pathways in Parkinson’s Disease Through Bioinformatics Analysis

Integrative transcriptomics identified conserved central-peripheral signatures in PD and five hub genes are candidate biomarkers/therapeutic targets, offering a systems-level framework for disease mechanisms and independent cohort validation.

Ehsan Lotfi, Arsh Ketabforoush, Fereshteh Azeditehrani et al. · Bioinformatics and Biology I... · 0 citations

Review Aug 2026

Mechanisms of Resistance to Immune Checkpoint Inhibitors and Therapeutic Strategies to Overcome Them: An Integrative Review.

Immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1, CTLA-4, and LAG-3 have transformed cancer therapy, but resistance limits durable benefit. This integrative review summarizes primary, adaptive, and acquired resistance driven by tumor-intrinsic defects, suppressive tumor microenvironmental programs, and host-re...

Ehsan Lotfi, F. Golab · Cancer Investigation · 0 citations