Open access
Jul 2026
METTL3 modulates cell viability and motility in HCC1143 and MDA-MB-231 triple-negative breast cancer cells
It is discovered that METTL3 depletion uniquely triggers a severe halt in cell division in HCC1143 cells, while universally disrupting actin-associated cell motility across different backgrounds, demonstrating that METTL3 acts as a context-dependent modulator of cell fate rather than a monolithic driver.
Buket Sağlam-Şen, Azime Akçaöz-Alasar, Ahmet Batuhan Dondurur et al.
· bioRxiv · 0 citations