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Author

Ekrem Akbulut

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Open access Aug 2026

Helicase Mutations in United States Isolates of SARS-CoV-2 Altered Protein Stability and Binding Dynamics

The concurrent occurrence of reduced predicted protein stability and more favorable docking-derived nucleic acid interface scores suggests that these mutations may influence helicase–nucleic acid recognition; however, direct effects on viral replication kinetics require experimental validation.

Ekrem Akbulut, Mehmet Emin Alhan · 0 citations