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Author

Elena Bisotto

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Open access Oct 2026

SRSF1 coordinates transcription and alternative splicing to modulate p53 and genome-maintenance

Serine/arginine-rich splicing factor 1 (SRSF1) regulates alternative splicing and acts as a proto-oncogene, but its role in transcription remains poorly defined. We combined time-course RNA-seq with experimental validation to define SRSF1-dependent transcriptional and splicing programs. We validated 67 of 143 alternati...

Sean Paz, Elena Bisotto, Massimo Caputi · 0 citations

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