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Elena Causa

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Open access Sep 2026

Better than hiding: high-grade glioma cells remodel the immune microenvironment to suppress cytotoxic immunity

Gliomas are aggressive brain tumors that progressively acquire a profound immune-evasive phenotype during malignant evolution. However, the mechanisms driving this transition from immune surveillance to immune tolerance are only partially understood. We used a PDGF-B-driven murine model in which sequential low- and...

Francesca Piaggio, Giorgia Guccione, Davide Ceresa et al. · 0 citations

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